Endogenous antioxidant defenses are regulated by Nrf2, which, in turn, is activated by a large number of naturally derived antioxidant-like compounds.23 N-acetylcysteine (NAC), a derivative of the naturally occurring amino acid cysteine (amino acids are the building blocks of proteins) has been found to be a potent activator of Nrf2.24-27 Conversely, NAC suppresses NF-kΒ and attenuates the body’s inflammatory cascade.28;29 Through this dual role NAC, like many other cell signalling nutrients, is able to regulate the expression of a wide array of genes responsible for the overall health of the cell. Supplementation with NAC consequently exerts favourable effects on vascular health, muscle strength, cell-mediated immunity, bone density, prevention of cognitive function, and the mitigation of nerve degeneration.30
NutriSearch Corporation is a Canadian company specializing in nutrition and health research, focussed primarily on multiple vitamin and mineral supplementation.
Our main product is the NutriSearch Comparative Guide to Nutritional Supplements™, which examines current research on the health benefits of supplementation for prevention of degenerative disease. The guide also includes comparisons of broad-spectrum supplements available in various markets around the world, is available in various regions. The guide for the Americas includes product comparisons from Canada, Colombia, México, and the United States. We also publish a guide for Australia and New Zealand.
NutriSearch is also available as a consultant to nutritional supplement manufacturers wanting to improve their supplements.